DMD! primarily follows the father-daughter relationship between Gen and Ann, heavily influenced by Gen's passion for tabletop roleplaying games, which drives his and his party's vivid imaginations.

As the story progresses, the characters primarily engage with trends of the current era, often in a comedic and lighthearted manner. However, the narrative also delivers poignant moments, addressing some heavy topics. The characters may also confront personal challenges that contribute to their growth and transformation.